GHK-Cu (Copper Tripeptide-1) is a synthetic preparation of the naturally occurring copper-binding tripeptide glycyl-L-histidyl-L-lysine (GHK), composed of three amino acids with a molecular weight of approximately 340.38 Da. When complexed with divalent copper (Cu²⁺), GHK-Cu forms a stable peptide-copper complex that has become a well-characterized compound in peptide chemistry and biochemical research.

GHK-Cu has been extensively characterized in the scientific literature for its interaction with copper ions and serves as a widely recognized research tool for investigating metal-peptide coordination chemistry, peptide-protein interactions, cellular signaling, and structure-activity relationships. Its defined molecular structure and unique copper-binding properties have made it a frequently studied peptide in experimental research settings.